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KMID : 0363220070450030271
Korean Journal of Dermatology
2007 Volume.45 No. 3 p.271 ~ p.274
A Serial Occurrence of Acute Generalized Exanthematous Pustulosis in Childhood Siblings
Goo Ja-Woong

Choi Eung-Ho
Abstract
Acute generalized exanthematous pustulosis (AGEP) is clinically characterized by the abrupt onset of erythema, non-follicular superficial pustules, fever and rapid spontaneous healing. Other findings such as peripheral neutrophilia and histologically neutrophilic spongiosis and microabscess also suggest AGEP. Its cause was focused on drug and viral infection, but the latter lacks objective evidence as a causative factor. We report two cases of AGEP that serially occurred in siblings without obvious drug history, which strongly suggests there is a possibility that AGEP could be caused by viral infection.
KEYWORD
Acute generalized exanthematous pustulosis, Siblings, Viral infection
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